Okay, I've been wondering this for a while now, but I think the Major Antagonists tag and future villains that qualify should be put to more scrutiny, like we did with the Minor Characters purge a few weeks back.
There are a few in there currently that don't even make sense, like Donatello Versus tagged as Major when his page itself lists Minor Antagonist; one who really didn't have any impact on the story aside from being a son of DIO. But that's just my opinion.
I honestly think characters like Wamuu, Enya and Diego should be the basis for Major Antagonists. As in, they have to have a MAJOR impact on the story and appear for more than a story arc. That's why I personally removed Damo from the tag, as despite being the one who killed Kira and unintentionally helped Gappy become fused, he never appeared once before that arc, got killed off within said arc and is now revealed to not even be in charge of the Rokakaka smuggling ring.
But I want to hear from you all so we can discuss and decide together rather than getting into eventual edit wars.